Clinical Trials
Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)
Study Status: Recruiting
Pregnant women with a primary diagnosis of posttraumatic stress disorder (PTSD) (PTSD Checklist for DSM-5 (PCL-5) score > 33) will be randomized to receive conventional cognitive processing therapy (CPT) (60-min session once/week for 12 weeks) or massed CPT (mCPT) (an intensive schedule of 12 60-min sessions over 5 days, approximately 2-3 sessions per day) via telemedicine, for treatment of PTSD. The research aims will be three-fold: (1) Evaluate the relative efficacy and tolerability of CPT vs. mCPT for treatment of perinatal PTSD and depression; (2) Determine the effect of CPT upon maternal-infant attachment and interaction; (3) Collect pilot data of obstetric and neonatal outcomes among those receiving the two CPT delivery schedules.
- Sex: FEMALE
- Minimum Age: 18 Years
- Maximum Age: 46 Years
Researchers look for people who fit a certain description, called eligibility criteria. Below are the inclusion and exclusion criteria for study participants:
Inclusion Criteria
- Female, ages 18-46, Pregnant (< 25 weeks), able to read and write in English, History of at least 1 criterion A trauma, Primary diagnosis of PTSD (confirmed by SCID), Psychotropic medications must be stable with no changes ≥ 2 weeks (≥ 6 weeks for fluoxetine), and no medication changes can be made during the course of therapy
Exlusion Criteria
- Not currently pregnant, Diagnosis of bipolar disorder, psychotic disorders, Suicidal ideation with plan or intent, Substance use disorder, Regular benzodiazepine use (> 4x weekly)
Conditions
The disease, disorder, syndrome, illness, or injury that is being studied.
Posttraumatic Stress Disorder (PTSD), PregnancyIntervention/Treatment
Intervention/Treatment
- BEHAVIORAL : Regular CPT
- BEHAVIORAL : Massed CPT
Sponsor
University of Texas at Austin
Principal Investigator(s)
- Erin Richardson, PRINCIPAL_INVESTIGATOR, University of Texas at Austin
Phase
- NA